Even if you’re Jeff Sessions or a Big Pharma exec, you know that CBD is taking the health and wellness world by storm. This article will help CBD newbies and experts alike understand why it provides relief for so many conditions and how to find a good supplier.
Although it’s new to many people today, Cannabis aka “Marijuana” has been used in Chinese medicine since 10,000 BC! How’s that for a track record? And despite whatever propaganda we’ve seen, it has always been safe–unlike synthetic drugs which are killing and poisoning people daily.
In the mid-1960s, western scientists identified CBD and THC — the two main cannabinoids present in the cannabis plant. THC (tetrahydrocannabinol) is a chemical compound that delivers the “high” that occurs from ingesting cannabis.
CBD, on the other hand, cannot make you psychoactive or “high.” Rather, this compound has much of the non-psychoactive properties of Medical Marijuana. In fact, you can use CBD to counteract THC’s mind-altering effects. Pretty amazing that the plant has a built-in safety mechanism!
Since the 60’s, over 400 individual cannabinoids have been discovered which show great symptom-relieving and disease-fighting abilities. They each have distinctly different effects within the body, and different potential uses for health and disease.
CBD, however, has captured the most attention for its wide-ranging health benefits. At our clinics across Florida we’ve seen thousands of lives positively impacted by this miraculous substance.
Here are six ways CBD could help you live a better life:
CBD May Help You Sleep
“Almost every clinical study that’s looked at cannabis-based medicines has shown an improvement in sleep. To say otherwise is to be staring in a deep hole — a deep hole of ignorance.” Dr. Ethan Russo, world renowned cannabis researcher.
Sleep disorders are pervasive, and 25%-30% of adults in the US have a disorder that results in some impact on their lifespan and overall health. From jet lag, restless leg syndrome, sleep apnea, narcolepsy to the most common — insomnia — our ability to get a good night’s sleep can be challenging. It’s also deadly. Heart disease, obsesity, diabetes, and a long list of ailements trace their roots to poor quality sleep.
Anxiety, stress, and depression are some of the most common causes of chronic insomnia. The majority of us have trouble sleeping sometimes. This is even more likely, though, if you have PTSD. You may already know that trouble sleeping and nightmares are two awful symptoms of PTSD.
In these uncertain and stressful times, most of us probably fall somewhere on the PTSD spectrum. You don’t have to have fought in a war to suffer from the traumas of modern day life.
Again, CBD will not get you high! It is as safe as the Omega 3 Oil or other health supplements that you might take. But it packs an incredibly powerful punch when it comes to sleep disorders–especially those related to PTSD.
In one study, in subjects with insomnia, daily use of CBD was associated with an increase in total sleep time and less frequent awakenings. Daily CBD doses were shown to reduce dream recall and did not cause ‘hangover’ effects compared to placebo. (Nicholson AN, Turner C, Stone BM, Robson PJ. Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early morning behavior in young adults. Journal of Clinical Psychopharmacology, 2004)
More recently, a study in 2014 investigated the effects of daily doses of CBD in patients with Parkinson’s disease and found a reduction in symptoms of REM sleep behavior disorder. After discontinuation of the drug, the frequency of symptoms returned to baseline levels, prior to treatment with CBD. (Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients: a case series, Journal of Clinical Pharmacy and Therapeutics, 2014, NIH).
This has big implications in the treatment of PTSD, as a reduction in REM sleep reduces the nightmares associated with this condition.
Similarly, CBD-enriched extract was described as a safe treatment for reducing anxiety and improving sleep for patients with post-traumatic stress disorder. (Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report. Assistant Clinical Professor of Psychiatry at the University of Colorado School of Medicine, Fall 2016)
Other studies investigating cannabinoids and obstructive sleep apnea suggest that synthetic cannabinoids such as nabilone and dronabinol may have short-term benefit for sleep apnea due to their corrective effects on serotonin-influenced apneas. “CBD may hold promise for REM sleep behavior disorder and excessive daytime sleepiness, while nabilone may reduce nightmares associated with PTSD and may improve sleep among patients with chronic pain.” (Cannabis, Cannabinoids, and Sleep: a Review of the Literature, Current Psychiatry Reports, April 2017)
Related: PTSD, Medical Marijuana, and You
CBD Can Help with Anxiety
Although we’re waiting on major clinical trials, the National Institute on Drug Abuse is supportive:
“CBD has shown therapeutic efficacy in a range of animal models of anxiety and stress, reducing both behavioral and physiological (e.g., heart rate) measures of stress and anxiety.”
In this study, Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. (Neuropsychopharmacology, May 2011, NIH), scientists monitoring the anxiety levels of volunteers with Social Anxiety Disorder who had to give a mock public speech found that only one dose of CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alert in their anticipatory speech. In fact, the study found that the high levels of anxiety experienced by the placebo group were almost abolished in the CBD group.
“I think there’s good evidence to suggest that CBD could be an effective treatment of anxiety, addiction and other disorders,” says Dr. Esther Blessing, a psychiatrist and researcher at New York University. “These results suggest that CBD reduces anxiety in SAD and that this is related to its effects on activity in limbic and paralimbic brain areas.”
Now, with funding from the National Institutes of Health, Dr. Blessing is about to begin a clinical trial to test whether CBD can help people with post-traumatic stress disorder who also have moderate or severe alcohol use disorder.
And because anxiety and PTSD are often linked with addiction and substance abuse, another Phase 2 clinical trial is exploring whether CBD might help prevent relapse in opioid abusers by reducing cravings for the drug. The study is led by Yasmin Hurd, a neuroscientist who directs the Addiction Institute at the Mount Sinai School of Medicine.
It may seem counterintuitive that a component of marijuana could be useful in treating addiction to another drug. But using CBD is very different from using marijuana in the mainstream view of getting high. Though CBD is extracted from cannabis, it does not lead to altered perception and cognition.
In a recent study linking the two conditions, Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders. (British Journal of Pharmacology, Oct 2017, NIH), scientists found:
“Studies show that cannabidiol…reduces fear relevant to phobias and post-traumatic stress disorder. Cannabidiol does so by reducing fear expression acutely and by disrupting fear memory and enhancing fear extinction, both of which can result in a lasting reduction of learned fear. The findings suggest that cannabidiol reduces the expression of drug memories acutely and by disrupting their reconsolidation.”
Once again, the use of CBD to treat the precursors to our current scourge of addiction is a huge deal and must be further investigated to help end this heartbreaking epidemic.
Related: Medical Cannabis for Sleep Relief
CBD Has Been Known to Fight Cancer
This is some of the most exciting research and anecdotal evidence emerging in the Medical Marijuana movement…Is marijuana not only effective in reducing the side effects of cancer such as pain, nausea and wasting…but could it also possibly be an important component of curing it?
We know from both lab testing, where Medical Marijuana and specifically the cannabinoids THC and CBD, and in tests in animals, that they were shown to have antitumourigenic properties. In other words, THC and CBD inhibited the growth of tumors in five key ways:
- hasten cancer cell death or apoptosis
- stop cancer cells from multiplying
- reduce the ability of cancer cells to stick to other cells
- cut off cancer cells nutrient sources by inhibiting angiogenesis (the development of new blood vessels)
- halt metastasis
In this study, Cannabidiol inhibits angiogenesis by multiple mechanisms (British Journal of Pharmacology, Nov 2012) scientists concluded unequivocally that:
“CBD inhibits angiogenesis by multiple mechanisms. Its dual effect on both tumour and endothelial cells supports the hypothesis that CBD has potential as an effective agent in cancer therapy.”
This is huge! CBD has been shown to effectively starve the cancer cells which form tumors! Unfortunately, there have been no human trials as of yet because of the government’s militant stance — we kind of get tired of repeating this — yet many brave doctors, scientists and activists have been carrying the torch for decades. We are grateful to pioneers like Rick Simpson, Dr. Ethan Russo, Justin Kander, Dr. Jeffrey Hergenrather, Mara Gordon, Prof. Donald I. Abrams MD, Raphael Mechoulam and so many others including our own Dr. Mark Hashim who are tirelessly presenting proof.
Cancer-killing dosing regimens vary, but most doctors recommend a high dose combination of THC/CBD for cancer eradication with a maintenance program consisting of high daily doses of CBD Oil. For more information, the below video of Dr. Mark Hashim and Nick Garulay is recommended.
CBD Oil is an Anti-inflammatory and Fights Oxidative Stress
CBD is one of the most effective anti-inflammatory substances on Earth! It even beats out traditional options such as Vitamin C, Vitamin E and Omega 3 supplements! Government sponsored research undertaken in 1998 bore out this discovery and led to a federal patent on both THC and CBD.
“Cannabidiol (CBD) was more protective against glutamate neurotoxicity than either ascorbate (Vitamin C) or alpha-tocopherol (Vitamin E), indicating it to be a potent antioxidant. These data also suggest that the naturally occurring, nonpsychotropic cannabinoid, cannabidiol, may be a potentially useful therapeutic agent for the treatment of oxidative neurological disorders such as cerebral ischemia.” Cannabidiol and Delta9-tetrahydrocannabinol are neuroprotective antioxidants (Laboratory of Cellular and Molecular Regulation, National Institutes of Mental Health, 1998)
According to a more recent cannabis related study published by the National Institutes of Health, it is now understood that cannabinoids exert anti-inflammatory properties as they go the extra mile in reducing the activity of the pathway most important to the inflammatory process. (Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis, The Journal of Pharamcology and Experimental Therapeutics, June 2018, NIH).
Furthermore, cannabinoids help stop inflammation as they contain beta-carophyllene, a terpene found in a variety of plants which are used for inflammatory diets.
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (Free Radical Biology & Medicine, Sep 2011)
“However, growing evidence suggests that the endocannabinoid system, which includes the CB₁ and CB₂ receptors, may be an area that is ripe for therapeutic exploitation. In this context, the related nonpsychotropic cannabinoid cannabidiol, which may interact with the endocannabinoid system but has actions that are distinct, offers promise as a prototype for anti-inflammatory drug development. This review discusses recent studies suggesting that cannabidiol may have utility in treating a number of human diseases and disorders now known to involve activation of the immune system and associated oxidative stress. These include rheumatoid arthritis, types 1 and 2 diabetes, atherosclerosis, Alzheimer disease, hypertension, the metabolic syndrome, ischemia-reperfusion injury, depression, and neuropathic pain.”
And in this study, Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis. (Plos One, 2011, NIH) CBD was found to be a “new” therapeutic strategy to treat inflammatory bowel diseases. The below video is of a My Florida Green patient who got incredible results with cannabis.
CBD Can Regulate Blood Pressure
According to an abstract from the, “Journal of Clinical Investigation,” Cannabidiol (CBD) was found to have numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress.
Nine healthy male volunteers were given CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study:
“Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress, particularly cold stress, and especially in the post-test periods. This may reflect the anxiolytic and analgesic effects of CBD, as well as any potential direct cardiovascular effects. … Further research is also required to establish whether CBD has any role in the treatment of cardiovascular disorders such as a hypertension.”
And further from the same study, A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study (Journal of Clinical Investigation, June 2017):
“These findings build upon previous research that shows CBD is a vasodilator, which means it makes your arteries and blood vessels wider, allowing for greater blood flow with less pressure. There is a growing body of medical research showing that CBD’s neuroprotective effects are beneficial with cardiovascular diseases, especially in recovery from stroke and heart attack.”
CBD Can Stabilize Blood Sugar
CBD is showing huge promise in treating blood sugar disorders, especially diabetes.
The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults. (The American Journal of Medicine, July 2013) We found that marijuana use was associated with lower levels of fasting insulin and HOMA-IR, and smaller waist circumference.
So CBD and medical cannabis could help you lose weight?! Well, there goes the idea that stoners with the munchies are getting fat!
In another study from the revolutionary Dr. Rapael Mechoulam: Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. (Journal of the American College of Cardiology, Dec 2010)…
“Remarkably, CBD attenuated myocardial dysfunction, cardiac fibrosis, oxidative/nitrative stress, inflammation, cell death, and interrelated signaling pathways. Furthermore, CBD also attenuated the high glucose-induced increased reactive oxygen species generation, nuclear factor-κB activation, and cell death in primary human cardiomyocytes. Collectively, these results coupled with the excellent safety and tolerability profile of CBD in humans, strongly suggest that it may have great therapeutic potential in the treatment of diabetic complications, and perhaps other cardiovascular disorders, by attenuating oxidative/nitrative stress, inflammation, cell death and fibrosis.
Cannabidiol lowers incidence of diabetes in non-obese diabetic mice. (Autoimmunity, June 2006) We now report that CBD treatment significantly reduces the incidence of diabetes in NOD mice from an incidence of 86% in non-treated control mice to an incidence of 30% in CBD-treated mice.
ISA Scientific, an Israeli company, recently signed a worldwide collaboration and licensing deal to establish therapies containing CBD.
In a statement, ISA Scientific Chief Executive Officer Mark J. Rosenfeld said:
“The licensing agreement is very well timed because our Phase 1 clinical trials on dosing and safety are now underway in Israel, and arrangements for Phase 2 trials on treating diabetes and chronic pain are in process. Unlike insulin and other existing medications for diabetes, CBD may actually suppress, reverse and perhaps cure the disease,” Rosenfeld added.
Which CBD Product Is For Me?
With all of the attention CBD is getting, countless companies are coming to market. Many are making great products with good intentions and fair pricing. Unfortunately, many more are over-priced junk. If you’re shopping for CBD here are a few key questions:
- Is it organic?
- We should all be eating pesticide-free food. This is especially true with CBD. Most CBD products on the market are CBD “isolates” that come from industrial Chinese farms. These have very high risks of having toxic pesticides and heavy metals.
- Is it full spectrum?
- If you’ve read previous blog posts about “the entourage effect” of cannabinoids, you know that 1+1 can equal 4. They work together in a song, and you need multiples notes to make music. Isolate products lose potency quickly, and will never be as effective as a full-spectrum.
- Does the label list specific CBD milligrams or “Hemp Oil”?
- At our Florida Medical Marijuana Certification Centers, we are seeing tons of CBD products from new patients. Some are from Amazon, some from health food stores, and many are from well-known brands like the Charlotte’s Web, the Stanley Brothers, and Green Roads. We won’t call our the perpetrators by name, but some brands are marketing low-CBD “hemp oil” or “hemp aerial parts” in oil as a CBD extract. This is false advertising and is a criminal offense in our opinion. Make sure your CBD has specific milligram quantities listed on the bottle!
- Does it taste good?
- Medicine shouldn’t hurt your taste buds. If it’s gross, it’s either rancid (very common) or it’s made by people who don’t care enough about their customers to make a quality product. Do you want to support either of those businesses?
- Are there 3rd party tests for purity?
- If you’re buying products without hard data, you are at risk of being deceived or ingesting toxic chemicals.
Our CBD Recommendation: RevitaOil
As thousands of our patients know, RevitaOil works! It comes straight from our organic farm in Colorado Springs, CO to Naples, FL where we label it ourselves.
As you should expect, bottles range from 350mg to 3000mg of CBD, it’s all organic, has a full-spectrum of cannabinoids, comes in a delicious mint flavor, and has full panel test results.
We are seeing amazing results and we hope you experience this medicine for yourself! For more information watch the below video from My Florida Green’s Dr. Mark Hashim or go to RevitaOil.com.